Please note: If you switch to a different device, you may be asked to login again with only your ACS ID. Journal of Heterocyclic Chemistry Desymmetrization of Cyclohexa-2,5-dienes through a Diastereoselective Protonation−Hydroamination Cascade. Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Andrew C. Flick, Maria José Arevalo Caballero and Albert Padwa. Require these words, in this exact order. Search 28 publications. Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly. Birch reduction of furo[3,2-c]pyridine (1c)[4] using 3.3 equivalents of sodium metal also gave three products (in 50% total yield), 3-ethynyl-4-pyridinol (2c), 3-ethyl-4pyridinol (4c), and 2,3-dihydrofuro[3,2-c]pyridine (5c) in the ratio of 1:6:2. 21! Crossref. Get article recommendations from ACS based on references in your Mendeley library. redistribute this material, requesters must process their own requests via the RightsLink permission Stereoselective Synthesis of Chiral 2,3-Disubstituted 2,3-Dihydro-4(1 Bookmark this article. However, a selective reduction that yields cyclohexadienes is also possible when employing a reaction with a one-electron transfer mechanism, the Birch reduction. Regioselectivity of Birch reduction:! Birch Reduction. Enjoy affordable access to Synthetic Studies of Substituted Pyridine Aldehydes as Intermediates for the Synthesis of Toddaquinoline, Its Derivatives and Other Natural Products. Utilization of a Michael Addition: Dipolar Cycloaddition Cascade for the Synthesis of (±)-Cylindricine C. Raphaël Lebeuf,, Frédéric Robert,, Kurt Schenk, and. Chihiro Tsukano, Atsuko Oimura, Iderbat Enkhtaivan, and Yoshiji Takemoto . Six-membered ring systems: pyridines and benzo derivatives. The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Concepción González-Bello, Luis Castedo. Raphaël Lebeuf,, Frédéric Robert, and. Dihydropyridine Preparation and Application in the Synthesis of Pyridine Derivatives. Clicking on the donut icon will load a page at with additional details about the score and the social media presence for the given article. without permission from the American Chemical Society. Select data courtesy of the U.S. National Library of Medicine. All DeepDyve websites use cookies to improve your online experience. Intramolecular Hydride Addition to Pyridinium Salts: New Routes to Enantiopure Dihydropyridones. The American Chemical Society holds a copyright ownership interest in any copyrightable Supporting Bahjat A. Saeed, Wisam A. Radhi, Rita S. Elias. 2,3-Bis(phenylsulfonyl)-1,3-butadiene-mediated syntheses of piperidone derivatives. Subbiah Sowmiah, José M. S. S. Esperança, Luís P. N. Rebelo, Carlos A. M. Afonso. The kinetics of pyridine hydrogenation was studied at high hydrogen pressures on a Mo-Al oxide and a Co-Mo-Al oxide catalyst. In all cases, the Birch reduction of furopyridine yielded ethynylpyridiols 2 and ethylpyridinols 4. Regioselectivity of Birch Reductive Alkylation of Biaryls. The Birch Reduction offers access to substituted 1,4-cyclohexadienes. DeepDyve's default query mode: search by keyword or DOI. To subscribe to email alerts, please log in first, or sign up for a DeepDyve account if you don’t already have one. - Protonation favoured at C-4 as leaves a radical stabilised by conjugation with the carbonyl group.! Include any more information that will help us locate the issue and fix it faster for you. - Electron withdrawing groups promote ipso, para reduction. Timothy J. Donohoe, Matthew J. Connolly, Akshat H. Rathi, and Lesley Walton . Thanks for helping us catch any problems with articles on DeepDyve. XXXI . Find more information about Crossref citation counts. from the ACS website, either in whole or in part, in either machine-readable form or any other form Mechanism of the Birch Reduction. Information about how to use the RightsLink permission system can be found at This article is cited by the Altmetric Attention Score and how the score is calculated. D.L. Electronic Supporting Information files are available without a subscription to ACS Web Editions. All the latest content is available, no embargo periods. Timothy J. Donohoe, Dale J. Johnson, Laura H. Mace, Mark J. Bamford, Osamu Ichihara. The rate equation was found to be r = kP pyr P H2 n P pyro, in which n is 1.5 at 300 and 375 °C and 1.0 at 250 °C. Timothy J. Donohoe, Matthew J. Connolly and Lesley Walton. The addition of two electrons to a pyridinium salt turns it into a nucleophile. Read and print from thousands of top scholarly journals. Check all that apply - Please note that only the first page is available if you have not selected a reading option after clicking "Read Article".