Glucosamine is thus marketed as an alternative medicine to treat osteoarthritis. Such tablets may hence contain almost 30% salt! There is no need for glucosamine hydrochloride to be stabilized with salt. In addition, commercially available glucosamine sulfate is glucosamine HCl with 2KCl (potassium sulfate) added to the mixture. Besides, I found out that people also use them for. Glucosamine sulfate and glucosamine hydrochloride are both salts of glucosamine. This website uses cookies to improve your experience. Your email address will not be published. On the other hand, glucosamine HCl didn’t have any real results in OA or knee pain. The hydrochloride or sulphate acid salt is purely a delivery vehicle in which we absorb it. With hundreds of thousands of knee replacements performed in 2014, there’s plenty of emerging research on various treatment approaches for those aching knees. Muller-Fabbender H, Bach GL, Haase W, Rovati LC, Setnikar I. Glucosamine sulfate compared to ibuprofen in osteoarthritis of the knee. Which of these 2 forms worked better for me? Company Registration Number: 07938681 Curr Med Res Opin 1980;7:110-14. Glucosamine kan mogelijk de pijn wat verlichten en het functioneren van de knie wat verbeteren. Glucosamine HCl does not. *These statements have not been evaluated by the F.D.A. Which Works Better? These are both trustworthy websites and they claim glucosamine sulfate is better because of the sulfur. The pH of a fluid is also what dictates whether a particular substance will dissolve in it or not. In addition, if a person clicks on this unique URL and then later visits USANA.com and makes a purchase (within 30 days), you receive credit for the sale. Maybe they have for years and have gotten progressively worse from the…, The phrase “living with knee pain” can mean different things to different people. Nonetheless, we embarked on clinical research to prove the efficacy of the hydrochloride form. NOTE:  After absorption, the sulfate ions enter the blood stream where a steady level already exists. This leads to breakdown of the glucosamine molecule and a pure glucosamine tablet would not show therapeutic effect. Enough research has been performed to reasonably conclude this. I’ve tried it myself, and it’s the substance that helped me most. Which of them is cheaper for the producers? One of the discussions you may have researched would be taking glucosamine sulfate vs glucosamine HCL (hydrochloride). †Testimonials are from actual users of Systems4Knees™. There are two forms of glucosamine - sulphate and hydrochloride. Send all comments or additions to: Frankp@chiro.org NOTE: This is a statement prepared by a manufacturer of Glucosamine hydrochloride, whose name is withheld to avoid the suggestion that I am recommending a specific brand of product.The intent of this page is informational only. The two different salts of glucosamine available in the market, viz. Hi Debbie, I deleted the link due to broken link issues. Also, a study in 2013 linked glucosamine sulfate with an … Er is onvoldoende bewijs om vóór of tegen het gebruik te pleiten voor de behandeling van knieartrose. Well, we're looking for good writers who want to spread the word. Hi Heather, I researched this topic last year when looking for help and relief for my OA knee issues. De meest gebruikte zijn glucosamine sulfaat en glucosamine … Er zijn verschillende vormen van glucosamine. Read How do you know what you should do or take? So, in the event that the sulfate moeity has anything to do with the benefit (which it […] Crystalline glucosamine sulphate (Dona ®) or glucosamine hydrochloride was administered at a dose of 20 mg/kg by either intravenous (IV) injection or nasogastric (NG) intubation.Plasma samples were collected before dosing and at 5, 15, 30, 60, 120, 360, 480 and 720 min after dosing. This is the reason why I always prefer supplements with glucosamine sulfate. Therapeutic activity of oral glucosamine sulfate in osteoarthritis: A placebo-controlled, double-blind investigation. Other clinical studies After all, they’re both. Sign up to receive the latest and greatest articles from our site automatically each week (give or take)...right to your inbox. The pH of a fluid is what makes it acidic, alkaline or neutral. In light of the increasing number of alternative therapies and 'me-too' drugs to treat a disease, it becomes important to know which is the best drug available in the market. Your email address will not be published. Powered by  - Designed with the Hueman theme, Glucosamine is probably the best ingredient for osteoarthritis. These cookies do not store any personal information. Read on to get a comparative account of glucosamine sulfate and glucosamine HCl…. It is important to know how a drug acts once it enters your body. Scientific evidence does not show that a glucosamine-chondroitin combination is any more effective than glucosamine by itself. The Natural Medicines Comprehensive Database rates the effectiveness of substances based on scientific evidence. Here’s how it works: When the link is clicked, a cookie (if allowed) is created. Also, what kind of glucosamine supplements have a better price? Glucosamine hydrochloride can provide the same benefits as glucosamine sulphate but is more efficient and does not process high sodium content. Shopping buttons on applicable product pages will appear to the referred user. In addition to this we only use pharmaceutical grade Glucosamine which is 99% pure to ensure the highest possible yield of active Glucosamine. Glucosamine Sulfate: The main problem with glucosamine sulfate tablets is that they need to be additionally stabilized using either sodium chloride (NaCl) or potassium chloride (KCl) salt. Required fields are marked *. Glucosamine sulfate is way better than the HCl form. While most published research has been done using glucosamine sulfate, the studies using glucosamine HCl have yielded similar results. All rights reserved. At this chapter, it’s really simple. This is a consideration for individuals who want to reduce their dietary intake of sodium. Clin Ther 1980;3:260-72, Pujalte JM, Llavore EP, Ylescupidez FR. It does not matter to the body in what form it receives the glucosamine, because eventually the actual active ingredient of the tablet is the pure glucosamine. It could well be only in your head, if you think one of the forms gives you better relief! Glucosamine Sulfate vs Glucosamine HClWhile most published research has been done using glucosamine sulfate, the studies using glucosamine HCl have yielded similar results. We also use third-party cookies that help us analyze and understand how you use this website. A ball and stick model of glucosamine. Paid model spokespeople may be used for illustrative purposes only. J Rheumatology 1998; 25 (supplemement 52): 8, Noack W, Fischer M, Forster KK, Rovati LC, Setnikar I. However, apart from the above glitch, a comparison between the therapeutic effects of the above two forms of glucosamine reveals no significant difference. Trademark number: 2456091 Hydrochloride offers a more concentrated form of glucosamine. Out of these cookies, the cookies that are categorized as necessary are stored on your browser as they are essential for the working of basic functionalities of the website. Which of these forms has a higher purity? Glucosamine Hydrochloride yields around 30% more active Glucosamine than a Sulphate form. A tablet or pill taken orally reaches the stomach and is immediately exposed to an acidic environment. Website © Amasci Creative Limited, website design Milton Keynes 2016 - 2020. In this clutter or ‘me-too’ drugs, how does one choose the right drug for him/her? What Companies Offer the Best Paleo Meal Delivery Service? It is estimated that nearly 80 percent of Americans 50 years and older show some signs of joint destruction on x …