AbdelRahman A. Dahy, Nobuaki Koga, A computational study on the formation of pyridin-2(1H)-one and pyridine-2(1H)-thione from the reaction of cobaltacyclopentadiene with isocyanate and isothiocyanate, Journal of Organometallic Chemistry, 10.1016/j.jorganchem.2014.08.008, 770, (101-115), (2014). Synthesis of pyridine bases by the chichibabin method (review). 12, 1587 (1975). Chemistry of Heterocyclic Compounds M. Wiess, J. R. M. Faskhutdinov, N. G. Pashkurov, https://doi.org/10.1007/BF01165434, Over 10 million scientific documents at your fingertips. and modeling of the electronic properties of the latter in order to obtain advanced materials for nanoelectronics. Geterotsikl. 1134; Chem. Nauchn. Abs., 47, 2685 (1953). Read and print from thousands of top scholarly journals. Yu. Do not surround your terms in double-quotes ("") in this field. Geterotsikl. Shulaeva, Khimiya v Sel'skom Khoz., No. Obshch.,54, 611 (1924). All rights reserved. For the ideal wavelength range (350−500 nm), lamps as well as sunlight can be used. 61-53265; Ref. T. Motoda, J. Chem. Khim. Prikl. Obshch.,54, 428 (1924). Tekhnol.,34, 102 (1991). Synthesis of Complex Pyridine Bases by the Reaction of v‐Cyano‐α‐acetylenes with Acetylene Catalyzed by Cobalt Complexes. All content in this area was uploaded by Usein M Dzhemilev. T. S. Sirlibaev A. Ikramov C. E. Nurmanov and N. O. Kholova Izv. Am. Nauk SSSR. Soc.,71, 2693 (1949). Khim., 13N135P (1964). Fiz. Khim., 5N166P (1974). Learn more about Institutional subscriptions. Abs.,45, 1628 (1951). Khim., 1N203P (1971). )-nitrileacetylenes with acetylene, catalyzed by cobalt complexes January 1986 Russian Chemical Bulletin 35(7):1478-1483 A. Abdurakhmanov, Author's Abstract of Thesis for Candidate of Chemical Sciences [in Russian], Tashkent (1974). Okadzaki, Japanese Patent No. Addition of Grignard reagents to pyridine N-oxides in THF at room temperature and subsequent treatment with acetic anhydride at 120°C afforded 2-substituted pyridines in good yields.By exchanging acetic anhydride for DMF in the second step, 2-substituted pyridine N-oxides were obtained, enabling the synthesis of 2,6-disubstituted pyridines. Khim.,37, 661 (1964). Abs.,51, 495 (1957). This leaves one unhybridized p orbital on each ring atom, which is perpendicular to the plane of the ring and parallel to other p orbitals. Ya. You can change your cookie settings through your browser. Soc.,74, 200 (1952). Fiz. Abs.,49, 2683 (1955). L. I. Vereshchagin and L L. Kotlyarevskii, Inventor's Certificate No. S. Yasuda and N. Abé, Japanese Patent Application No. F. Frank and R. Seven, J. B. Shaw, J. Chem. Data Ser.,2, 76 (1957). R. Graf and W. Lander, J. Prakt. Zh. 2,449,340; Ref. Fiz. et al. Soc.,54, 1921 (1923). A. Nenz and M. Pieroni, Hydrocarbon Process,47, 139 (1968). Khim.,30, 982 (1961). Synthesis of complex pyridine bases in the reaction of ??,?? To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one. Khim., No. I. Gelas, Bull. 16. Abstracts [in Russian], (1991), Vol. K. K. Moll, Chem. Prikl. 2-Vinylpyridine is an organic compound with the formula CH 2 CHC 5 H 4 N. It is a derivative of pyridine with a vinyl group in the 2-position, next to the nitrogen. Khim., 7N183 (1987). February, 1996. The cyclo-oligomerization of several terminal and internal alkynes under phase transfer conditions by the RhCl3-Aliquat® 336 catalyst is described. Russk. K. Fudzii, Sumitomo Kagaku, No. The kinetics of 1-heptyne cyclotrimerization at 90 °C in 1,1,2,2-tetrachloroethane/water were found to follow the second-order rate law d[arene]/dt = −k[alkyne][RhCl3] when the molar ratio of substrate:rhodium chloride:quat was approximately 25:1:1. Prikl. One approach aimed at solving this problem involv, Project goal: the establishment of a mechanism of catalytic reactions involving metal complex catalysts. D. S. Petrenko, G. P. Geid, and V. A. Leites, Koks i Khimiya, No. 2,766,248, Ref. In recent reviews [13,14] acetylene is compared with ethylene. Izobr., No. Zh. Am. The process is of historic interest as well as being applicable to organic synthesis. Akad. Zh. A disubstituted acetylene can be prepared from a monosubstituted Submitting a report will send us an email through our customer support system. Planned by the project research in this area will help to develop a new efficient synthesis route to lembehynes and their derivatives and widely explore the influence of the nature and structure of the substituents in lembehyne, the introduction of additional functional groups on the developing neuriogenic activity, and thus give the opportunity to spend a full cycle of pre-clinical trials of the most promising samples lembehynes given structure. Published data on the synthesis of pyridine bases from carbonyl compounds or acetylene and ammonia by the Chichibabin method are summarized. Zh. 1,208,569, Ref. Unlimited access to over18 million full-text articles. Khim., 5N167P (1974). K. N. Akhmerov, D. Yusupov, A. Abdrakhmanov, and A. Rakhmatova, and Sh. 121,794; Byull. Zh. Khim., 61927P (1958). J. Falz, J. E. Mahan, and D. White, Petrol. The collaborative research would allow extensive investigations into understanding the influence of the nature and structure of substituents in the dienoic acids, the introduction of additional functional substituents and various compounds of the “mitocan” group, as well as the location of the 5Z,9Z-dienic system position towards the carboxylic moiety on the antitumor activity. Zh. Khim. Eng. Obshch.,47, 703 (1915). Ztg.,45, 159 (1942); Chem. Zh. We'll do our best to fix them. 896,648; Chem. Khim. Rusk. PubMed Google Scholar. Zh. H. Krzikalla, German Patent No. 2,749,348; Ref. Omaé, Kh. Process Engl.,17, 9 (1971). M. Ferles and J. Jizba, J. Chemie Pyridinu, Prague (1957). Vuzov. Zh.,1, 3 (1994). Described in the literature methods and approaches to synthesize this class of compounds are known to be multistage, require the use of expensive and hard-to-reach reagents, and, most importantly, these techniques do not allow obtaining these acids with a high degree of stereo purity significantly complicating the research in this area. Chem.,107, 145 (1924). N. A. Titova, G. N. Abaev, V. V. Vetrova, B. F. Ustavshchikov, and G. K. Denisova, Zh. Khim., 40881 (1956). Otd. Okadzaki, and E. Sano, Japanese Patent No. Khim., 12N215P (1975). The search and study into mechanisms of action of the new and well known preparations are performed by using constantly expanding set of novel potentially promising compounds. Chem.,47, 789 (1955). J. E. Mahan, U. S. Patent No. J. E. Mahan and C. E. Becker, U. S. Patent No. Soc. slated from Khimiya Geterotsiklicheskilch Soedinenii, No. F. Stitz, Osterr. Vereshchagin and I. L. Kotlyarevskii, Inventor's Certificate No. E. Kobayashi, Japanese Patent No. Zh. Ind. Soc.,71, 2629 (1949). D. S. Petrenko, Pyridine and Quinoline Bases [in Russian], Metallurgiya, Moscow (1973). Mukhammed, Carbonyl Compounds in the Synthesis of Heterocycles [in Russian], Saratov (1992), Part 2, p. 87. R. L. Frank and E. F. Riener, J. Zh. Khim., 68716P (1959). It is used industrially as a precursor to specialty polymers and as an intermediate in the chemical, pharmaceutical, dye, and photo industries. Khim., 18N99P (1972). 39,871; Ref. Soc. Ind. 6, 89 (1959). Zh. ) with olefins, allenes, and acetylenes were synthesized. As part of the proposed project with the above reaction, it is planned to develop common approaches to the stereoselective production of natural and synthetic lembehynes (lembehyn A, B, C), the study of their neuritogenic and cytotoxic properties on cell lines, as well as the study of patterns of structure activity. Khim., 90107P (1980). It’s your single place to instantly 3, 476 (1971). 2,698,849; Ref. Ser. Zh. K. R. Hargrave, British Patent No. Process,7, 1802 (1952). Obshch.,54, 413 (1924). Fiz. Fiz. 10, 2332 (1988). A. Avots, Catalytic Synthesis and Transformations of Heterocyclec Compounds [in Russian], Zinatne, Riga (1976), p. 93. ChemInform Obshch. Zap, Yaroslavskogo Tekhnologicheskogo Instituta,22, 42 (1973). 117,787; Byull. Akad. Geterotsikl. 2, p. 4. N. D. Rus'yanova, B. E. Kogan, and M. A. Kosareva, Khim. H. Baltz, K. K. Moll, H. J. Vebel, and M. Muhlstodt, GDR Patent No. R. Guilaumin, Ann. H. Beschke and H. Friedrich, German Patent No. 4, 61 (1980). Among these derivatives, there are compounds satisfying preclinical testing requirements and successfully overcame Preliminary Phase I-III Clinical Trials (22-methyl-5Z,9Z-haxacosadienoic acid, 14-methyl–5Z,9Z-pentadecadienoic acid, 23-methyl-5Z,9Z-tetracosadienoic acid) [Carballeira, N., 2008, Pommier et al., 2009, 2013]. We have used a Cu(I)-catalysed azide-alkyne cycloaddition click reaction to prepare the 1,2,3-triazole-linked diethynyl-pyridine amides. They were placed on your computer when you launched this website. 2,745,833; Ref. E. Dürkopf and H. Göttsch, Berichte,23, 685 (1890). Codimerization of v‐cyano‐α‐acetylenes (Ia), (Ib), or (VIII) with excess acetylene, catalyzed by cobalt 2‐ethylhexanoate, yields mixtures of the compounds (II) ‐ (IV), (V) ‐ (VII), or (IX) ‐ (XIII). Abs.,38, 2040 (1944).