(2002).  Many methods exist, such as: Metal hydrides are typically not used to reduce aryl nitro compounds to anilines because they tend to produce azo compounds. Water is the proton source. 0000001503 00000 n InChI = 1S/Zn Tetrahedron Letters, 25, 839–842. DOI:10.1016/s0040-4039(01)80041-1. Google Scholar. The reduction of aromatic nitro compounds with activated iron. There is a newer version of this article, I have read and accept the Wiley Online Library Terms and Conditions of Use. and you may need to create a new Wiley Online Library account. © 2020 Springer Nature Switzerland AG. Synthesis of (3-aminophenyl) acetylene via hydrogenation of (3-nitrophenyl)acetylene over cobalt polysulfide and ruthenium sulfide catalysts. Ultrasonically activated reduction of substituted nitrobenzenes to corresponding N-arylhydroxylamines. Synthesis of the male ant pheromone (E)-2,4-dimethyl-2-hexenoic acid was performed using this simple methodology. Contents. %PDF-1.3 %���� O’Neil, M. J. https://doi.org/10.2478/s11696-012-0195-6, DOI: https://doi.org/10.2478/s11696-012-0195-6, Over 10 million scientific documents at your fingertips, Not logged in 6398). 0000001754 00000 n Electrolytic reduction of organic compounds. Chem. Chemical Reviews, 102, 3667–3692. The reaction can also be effected through radical reaction with tributyltin hydride and a radical initiator, AIBN as an example. Gowda, D., Mahesh, B., & Shankare, G. (2001). 0000001067 00000 n For example, one could use: Hydrodenitration (replacement of a nitro group with hydrogen) is difficult to achieve but can be effected by catalytic hydrogenation over platinum on silica gel at high temperatures. When crude 11a was subjected to air oxidation, pyrazino[2',3':2,3;5',6':2,3]bis(5α-cholestane) (9) was obtained. DOI: 10.1021/cr00066a003. 27 0 obj << /Linearized 1 /O 30 /H [ 887 200 ] /L 34261 /E 7316 /N 8 /T 33603 >> endobj xref 27 14 0000000016 00000 n DOI: 10.1002/1521-3773(20001103)39:21<3772::AID-ANIE3772>3.0.CO;2-5. 1 Structures Expand … Unlimited viewing of the article PDF and any associated supplements and figures. Staiger, R. P., & Miller, E. B. 1968 Jul;24(14):5115-22. Chief, you describe the subject of your post as "Formic acid/Zinc Nitroalkene Reduction", but on both articles I can only find nitroalkane reductions, no mention of double bonds betting reduced. Liu, Y., Lu, Y., Prashad, M., Repic, O., & Blacklock, T. J. Google Scholar. Merck Index (pp. InChI = 1S/C2H4O2/c1‐2(3)4/h1H3,(H,3,4) Solvents for synthesis and catalysis. Sarmah, P., & Dutta, D. K. (2003). Chemical Papers �=S}%� (2005). Pookot Sunil Kumar. FMC (I) R&D Centre, Society for Innovation and Development, Indian Institute of Science Campus, 560012, Bangalore, India, Department of Chemistry, University of Mysore, Manasagangotri, 570006, Mysore, India, You can also search for this author in (AcOH) [64‐19‐7] C2H4O2 (MW 60.06) Purification: acid washing is not uncommon, but not always vital. Please check your email for instructions on resetting your password. Dupont, J., de Souza, R. F., & Suarez, P. A. Unlimited viewing of the article/chapter PDF and any associated supplements and figures. O’Neil, M. J. 462). The donor ether acts as a ligand and also serves as a co-solvent. A mild, environmentally friendly method for reduction of aromatic nitro group to amine is reported, using zinc powder in aqueous solutions of chelating ethers. IV. InChIKey = QTBSBXVTEAMEQO‐UHFFFAOYSA‐N, (reducing agent; causes reductive elimination of vicinal heteroatoms;2-15 cleaves heteroatom–heteroatom bonds;16-27 reduces allylic, benzylic, or α‐carbonyl‐substituted heteroatoms,28-34 activated carbonyls,35-37 and alkenes38-40).